Genomic Profiling of a Human Leukemic Monocytic Cell-Line (THP-1) Exposed to Alpha Particle Radiation

Table 2

Expression profiles of genes that were shown to be statistically significant 72 h after alpha-particle irradiation at all doses. Statistics based on an 𝑛=5 biological replicates.

Accession no.	Symbol	FC-D1	Pv	FC-D2	Pv	FC-D3	Pv
NM_001040021.1	CD14	3.15	0.00	5.50	0.00	5.89	0.00
NM_000582.2	SPP1	3.72	0.00	4.98	0.00	5.68	0.04
NM_021158.3	TRIB3	2.43	0.00	4.32	0.00	5.34	0.00
NM_000607.1	ORM1	2.49	0.00	3.62	0.00	3.67	0.00
NM_005980.2	S100P	2.28	0.00	3.25	0.00	3.44	0.00
NM_002965.2	S100A9	2.13	0.00	2.43	0.00	2.48	0.00
NM_002522.2	NPTX1	1.82	0.00	2.57	0.00	2.48	0.00
NM_006216.2	SERPINE2	1.75	0.00	2.51	0.00	2.44	0.00
NM_001122.2	ADFP	1.88	0.02	2.29	0.00	2.43	0.00
NM_005461.3	MAFB	1.86	0.01	2.36	0.00	2.41	0.00
NM_001995.2	ACSL1	1.55	0.00	2.34	0.00	2.34	0.00
NM_001375.2	DNASE2	1.66	0.01	2.05	0.00	2.22	0.00
NM_002964.3	S100A8	1.87	0.00	2.19	0.00	2.21	0.00
NM_000239.1	LYZ	2.08	0.00	2.26	0.00	2.19	0.00
NM_015869.4	PPARG	1.68	0.00	2.13	0.00	2.17	0.00
NM_019058.2	DDIT4	1.57	0.00	2.15	0.00	2.15	0.00
NM_000104.2	CYP1B1	1.82	0.00	2.15	0.00	2.13	0.00
NM_003380.2	VIM	1.56	0.00	2.20	0.00	2.10	0.00
NM_000584.2	IL8	2.01	0.01	2.07	0.00	2.07	0.01
NM_000632.3	ITGAM	1.83	0.00	2.07	0.00	2.06	0.00
NM_006366.2	CAP2	1.51	0.00	1.92	0.00	2.03	0.00
NM_002928.2	RGS16	1.54	0.00	1.66	0.00	1.98	0.00
NM_003376.4	VEGFA	1.54	0.00	2.03	0.00	1.97	0.00
NM_003916.3	AP1S2	1.60	0.00	2.01	0.00	1.97	0.00
NM_004811.1	LPXN	1.50	0.00	2.18	0.00	1.94	0.00
NM_174918.2	C19orf59	1.55	0.00	2.12	0.00	1.92	0.00
NM_013363.2	PCOLCE2	1.68	0.00	1.96	0.00	1.90	0.00
NM_000889.1	ITGB7	1.68	0.00	1.91	0.00	1.89	0.00
NM_001629.2	ALOX5AP	1.57	0.00	1.98	0.00	1.81	0.00
NR_002203.1	FTHL8	1.51	0.03	1.67	0.00	1.67	0.00
NM_018004.1	TMEM45A	1.53	0.01	1.92	0.00	1.60	0.00
NM_000265.4	NCF1	1.53	0.01	1.55	0.01	1.55	0.00
NM_003583.2	DYRK2	0.57	0.02	0.64	0.01	0.63	0.01
NM_152764.1	C16orf73	0.64	0.00	0.65	0.00	0.62	0.00
NM_001821.3	CHML	0.54	0.01	0.61	0.00	0.61	0.00
NM_002130.6	HMGCS1	0.54	0.01	0.56	0.00	0.61	0.00
NM_005640.1	TAF4B	0.56	0.01	0.66	0.01	0.61	0.03
NM_001005291.1	SREBF1	0.61	0.01	0.62	0.00	0.59	0.00
NM_001093772.1	KIT	0.58	0.00	0.60	0.00	0.57	0.00
NM_000527.2	LDLR	0.60	0.03	0.59	0.00	0.56	0.00
NM_000820.1	GAS6	0.62	0.02	0.64	0.00	0.54	0.00
NM_033445.2	HIST3H2A	0.48	0.02	0.58	0.04	0.54	0.02
NR_002771.1	DLEU2L	0.57	0.01	0.60	0.00	0.53	0.00
XR_001514.1	DLEU2	0.64	0.01	0.60	0.00	0.51	0.00
NM_005063.4	SCD	0.56	0.01	0.57	0.00	0.49	0.00
NM_001017369.1	SC4MOL	0.54	0.01	0.53	0.01	0.48	0.00
NM_000222.1	KIT	0.50	0.01	0.53	0.00	0.42	0.00
NM_198336.1	INSIG1	0.54	0.03	0.44	0.00	0.41	0.00