Genomic Profiling of a Human Leukemic Monocytic Cell-Line (THP-1) Exposed to Alpha Particle Radiation

Table 3

Expression profile of genes validated using qRT-PCR. Fold changes and associated 𝑃 values are indicated for both time points and all doses.

Accession no.	Symbol	0.5 Gy				1.0 Gy				1.5 Gy
		FC-T1	Pv	FC-T2	Pv	FC-T1	Pv	FC-T2	Pv	FC-T1	Pv	FC-T2	Pv
NM_000582	SPP1	10.865	1.2𝐸−05	16.3775	0.0164	15.48	4𝐸−04	21.56	0.0456	15.18	3𝐸−06	22.026	0.163
NM_000591	CD14	2.349	0.0011	7.8024	0	4.927	0.001	10.66	8𝐸−06	6.215	2𝐸−04	11.534	0.01
NM_002522	NPTX1	1.485	0.07025	3.1824	4𝐸−05	2.39	6𝐸−04	3.523	2𝐸−05	2.599	8𝐸−05	3.2643	0.008
NM_003380	VIM	1.2647	0.30111	2.3705	0.0161	1.248	0.271	2.965	0.0008	1.622	0.028	3.1475	0.004
NM_005461	MAFB	1.4789	0.15033	4.4038	0.0001	2.139	0.012	5.656	6𝐸−05	2.968	6𝐸−04	4.9452	0.017
NM_021158	TRIB3	2.0386	0.01668	3.2229	0.0002	5.729	3𝐸−04	5.373	0.0003	6.746	4𝐸−04	5.7073	3𝐸−04
NM_005542	INSIG1	−1.58	0.00271	−2.01	0.0228	−1.36	0.013	−2.56	0.001	−1.75	0.002	−2.89	6𝐸−04
NM_000222	KIT	−1.18	0.20533	−2.515	0.0101	−1.09	0.411	−3.22	0.0014	−1.49	0.014	−3.35	0.001
NM_005980	S100P	0.9565	0.66173	3.9682	4𝐸−06	1.371	0.067	4.48	2𝐸−06	1.632	0.002	4.5418	2𝐸−05
NM_000607	ORM1	1.0251	0.83691	4.5517	0.0003	1.406	0.048	6.452	0.0003	1.638	0.02	6.4402	5𝐸−04