Protection of the Extracts of Lentinus edodes Mycelia against Carbon-Tetrachloride-Induced Hepatic Injury in Rats
Figure 4
Effects of LEM on gene expressions of Mn-SOD, Cu/Zn-SOD, and glutathione peroxidase (GPx) in liver of CCl4-treated rats. (a) The representative picture showing mRNA levels for Mn-SOD, Cu/Zn-SOD, GPx, or β-actin in liver isolated from CCl4-induced rats receiving treatment with silymarin or LEM three times daily for 8 weeks. Lane 1: vehicle-treated Wistar rats; lane 2: vehicle-treated CCl4-induced rats; lane 3: silymarin- (200 mg/kg) treated CCl4-induced rats; lane 4: LEM- (100 mg/kg) treated CCl4-induced rats; lane 5: LEM- (200 mg/kg) treated CCl4-induced rats; lane 6: LEM- (500 mg/kg) treated CCl4-induced rats. (b) The representative response of protein level for Mn-SOD, Cu/Zn-SOD, GPx, or actin in liver isolated from CCl4-induced rats receiving treatment with silymarin or LEM three times daily for 8 weeks. All lanes are expressed as the same as mRNA level (a) on the above.
