Protection of the Extracts of Lentinus edodes Mycelia against Carbon-Tetrachloride-Induced Hepatic Injury in Rats

Table 1

The quantification of mRNA levels for Mn-SOD, Cu/Zn-SOD, GPx, or β-actin in liver isolated from CCl₄-induced rats receiving treatment with silymarin or LEM three times daily for 8 weeks. Quantification of mRNA levels using Mn-SOD/β-actin, Cu/Zn-SOD/β-actin, and GPx/β-actin was expressed as mean with standard error (SE) (𝑛=4 per group) in each group. *𝑃<0.05 compared with CCl₄-induced group receiving vehicle.

	Mn-SOD (arbitrary units); mRNA/β-actin	Cu/Zn-SOD (arbitrary units); mRNA/β-actin	GPx (arbitrary units); mRNA/β-actin
Control	1.31±0.11 *	1.20±0.08 *	1.91±0.17 *
CCl4	0.69±0.06	0.75±0.05	1.03±0.08
+ Silymarin
200 mg/kg	1.15±0.07 *	1.37±0.07 *	1.48±0.11 *
+ LEM
100 mg/kg	0.64±0.04	1.24±0.09 *	1.50±0.18 *
200 mg/kg	0.82±0.05 *	1.37±0.11 *	1.55±0.13 *
500 mg/kg	1.09±0.08 *	1.71±0.13 *	2.10±0.15 *