Research Article

Protection of the Extracts of Lentinus edodes Mycelia against Carbon-Tetrachloride-Induced Hepatic Injury in Rats

Table 2

The quantification of protein levels for Mn-SOD, Cu/Zn-SOD, GPx, or actin in liver isolated from CCl4-induced rats receiving treatment with silymarin or LEM three times daily for 8 weeks. Quantification of protein levels using Mn-SOD/actin, Cu/Zn-SOD/actin, and GPx/actin was expressed as mean with standard error (SE) ( 𝑛 = 4 per group) in each group. * 𝑃 < 0 . 0 5 compared with CCl4-induced group receiving vehicle.

Mn-SOD (arbitrary units)
protein/actin
Cu/Zn-SOD (arbitrary units)
protein/actin
GPx (arbitrary units)
protein/actin

Control 1 . 2 4 ± 0 . 0 7 * 1 . 4 2 ± 0 . 1 5 * 1 . 1 8 ± 0 . 0 8 *
CCl4 1 . 0 1 ± 0 . 0 4 1 . 0 2 ± 0 . 0 5 0 . 8 2 ± 0 . 0 6
+ Silymarin
 200 mg/kg 1 . 1 6 ± 0 . 0 5 * 1 . 6 0 ± 0 . 0 9 * 1 . 1 1 ± 0 . 0 5 *
+ LEM
 100 mg/kg 0 . 8 2 ± 0 . 0 6 0 . 9 1 ± 0 . 0 4 1 . 0 6 ± 0 . 0 5 *
 200 mg/kg 1 . 0 3 ± 0 . 1 1 1 . 0 7 ± 0 . 0 3 1 . 2 3 ± 0 . 1 4 *
 500 mg/kg 1 . 2 1 ± 0 . 1 0 * 1 . 6 7 ± 0 . 0 6 * 1 . 5 9 ± 0 . 1 7 *