Table of Contents Author Guidelines Submit a Manuscript
The Scientific World Journal
Volume 2012 (2012), Article ID 291395, 7 pages
Research Article

Impact of Cypermethrin on Fingerlings of Common Edible Carp (Labeo rohita)

1Natural Product Laboratory, Department of Zoology, D.D.U. Gorakhpur University, Gorakhpur 273009, India
2Department of Botany, D.D.U. Gorakhpur University, Gorakhpur 273009, India

Received 24 October 2011; Accepted 15 December 2011

Academic Editor: Carmina Montoliu

Copyright © 2012 Sudhanshu Tiwari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Laboratory evaluations were made to assess the toxicological and biochemical effect of cypermethrin on fingerlings of common edible freshwater culture carp (Labeo rohita). There was a significant negative ( 𝑃 < 0 . 0 5 ) correlation observed between effective doses of cypermethrin and exposure periods; that is, LC50 values decreased from 0.323 μg/L (6 h) to  > 0.278 μg/L (12 h),  > 0.240 μg/L (18 h) and >0.205 μg/L (24 h). Exposure to sublethal doses of cypermethrin for 24 h and 96 h exposure period caused significant ( 𝑃 < 0 . 0 5 ) time- and dose-dependent alterations in total protein, total free amino acids, nucleic acids, glycogen, pyruvate, and lactate level and in the activity of enzyme protease, alanine aminotransferase, aspartate aminotransferase, acid phosphatases, alkaline phosphatases, acetylcholinesterase, and cytochrome oxidase in liver and muscle tissues of fish. Thus, cypermethrin has potent piscicidal activity against fingerlings of fish Labeo rohita and adversely affects their behavioural patterns, shifting aerobic pathway of fish respiration towards anaerobic pathway and also inhibiting energy production by suppressing ATP synthesis.