The Design of New Adjuvants for Mucosal Immunity to Neisseria meningitidis B in Nasally Primed Neonatal Mice for Adult Immune Response

Table 2

Avidity index of IgG and IgM antibodies of immunized mice by intranasally and intramuscularly routes.

Routes	Unimmunized mice*		OMP+Stx1		OMP+Stx2		OMP+CT
	IgG	IgM	IgG	IgM	IgG	IgM	IgG	IgM
Intranasally	0.16	0.13	0.82	0.65	0.94	0.78	0.42	0.35
Intramuscularly	0.12	0.13	0.45	0.69	0.84	0.65	0.33	0.38

Avidity index values: <0.29: low avidity; 0.30–0.49: intermediate avidity; >0.50: high avidity.