LDL-Apheresis: Technical and Clinical Aspects

Table 6

LDL adsorption with dextran sulfate (Liposorber LA-15, Kaneka, Japan) in hypercholesterolemia (selection of literature).

Year	Authors	Diagnosis	Patients (𝑛)	Drop out	Therapy duration (years)	Side effects (%)	Outcome
1988	Thompson and Okabayashi [29]	FH, CHD	20	—	2.1	0.5	19 improved
1992	Gordon et al. [30]	FH	54	—	0.25	—	54 improved
1994	Daida et al. [31]	FH, CHD	66	—	1.0	—	45 improved
1996	Kroon et al. [32]	FH, CHD	21	—	2.0	1.3	21 improved
1997	Gordon and Saal [33]	FH, CHD	45	4	0.5	4.0	41 improved
	Bambauer et al. [34]	FH, CHD	120	35	6.0	2.2	85 improved
1998	Mabuchi et al. [35]	FH, CHD	130	—	6.0	—	94 improved
1999	Nishimura et al. [36]	FH	30	5	2.3	—	4 improved
	Richter et al. [37]	FH, CHD	8	—	3.0–5.0	—	6 improved
2003	Bambauer et al. [38]	FH, CHD	32	—	8.0	0.3	31 improved
2010	Moriarty et al. [39]	FH, CHD	10	—	0.5	—	10 improved