Research Article

Antitumor and Immunopotentiating Activity of Polysaccharide PST001 Isolated from the Seed Kernel of Tamarindus indica: An In Vivo Study in Mice

Table 7

Table showing the effect of PST001 on lymphocyte subsets.

ConcentrationCD3CD4CD8CD4/CD8 ratio

Control 5 9 . 5 1 ± 1 . 4 2 3 6 . 3 0 ± 0 . 8 4 2 0 . 1 7 ± 0 . 6 6 1.799
100 mg/kg 5 7 . 0 1 ± 1 . 0 ** 5 5 . 5 5 ± 0 . 9 1 *** 2 7 . 0 8 ± 1 . 0 1 *** 2.05
200 mg/kg 4 1 . 8 3 ± 0 . 9 4 *** 3 8 . 9 6 ± 0 . 4 8 *** 2 0 . 2 8 ± 0 . 5 3 ns1.92
400 mg/kg 3 1 . 6 9 ± 0 . 6 2 *** 3 0 . 4 8 ± 0 . 6 6 *** 2 2 . 6 2 ± 0 . 3 9 *** 1.34

Data were expressed as mean ± SD ( 𝑛 = 6 ) on day 15 of the experiment. Statistically significant differences are at * 𝑃 < 0 . 0 5 , ** 𝑃 < 0 . 0 1 , *** 𝑃 < 0 . 0 0 1 ; ns is the non-significant, as compared with control group.