Clinical Study

Long-Term Prospective Study of the Influence of Estrone Levels on Events in Postmenopausal Women with or at High Risk for Coronary Artery Disease

Table 1

Baseline clinical characteristics and comparison of estrone <15 pg/mL and estrone ≥15 pg/mL in 251 patients.

Baseline 𝑁 = 2 5 1 Estrone <15 pg/mL, 𝑁 = 4 3 (17%)Estrone ≥15 pg/mL, 𝑁 = 2 0 8 (83%) 𝑃

Age (years) 6 9 . 7 ± 7 . 0 7 2 ± 7 . 5 6 9 . 2 ± 6 . 7 0.016
Body mass index (kg/m2) 2 9 . 7 ± 5 . 3 2 7 . 9 ± 4 . 6 3 0 ± 5 . 4 0.020
Hypertension238 (95)38 (88)200 (96)0.036
Diabetes144 (57)16 (37)128 (62)0.003
Dyslipidemia233 (93)40 (93)193 (93)0.956
Family history170 (68)31 (72)139 (67)0.641
Coronary artery disease189 (75)35 (81)154 (74)0.308
Smoking25 (10)4 (10)21 (10)0.837
SBP (mm Hg) 1 4 1 . 8 ± 1 8 . 4 1 3 7 . 7 ± 2 1 . 2 1 4 2 . 6 ± 1 7 . 7 0.110
DBP (mm Hg) 8 3 ± 9 . 9 8 0 . 7 ± 1 0 . 8 8 3 . 5 ± 9 . 6 0.092
Triglycerides (mg/dL) 1 7 3 . 4 ± 1 1 6 . 1 1 4 8 . 9 ± 6 3 . 1 1 7 8 . 5 ± 1 2 3 . 8 0.023
Total cholesterol (mg/dL) 1 9 9 . 3 ± 4 1 . 1 2 0 0 . 7 ± 4 0 . 7 1 9 9 ± 4 1 . 2 0.808
HDL cholesterol (mg/dL) 5 2 . 8 ± 1 2 . 5 5 4 . 8 ± 1 3 . 1 5 2 . 4 ± 1 2 . 3 0.247
LDL cholesterol (mg/dL) 1 1 2 . 7 ± 3 6 1 1 6 . 1 ± 3 7 . 8 1 1 2 ± 3 5 . 7 0.496
Glucose (mg/dL) 1 3 2 . 2 ± 5 6 . 9 1 0 7 . 5 ± 3 2 . 8 1 3 7 . 3 ± 5 9 . 5 0.002
C reactive protein (mg/dL) 0 . 6 5 ± 1 . 2 2 0 . 4 5 ± 0 . 5 5 0 . 7 0 ± 1 . 3 1 0.045
Estrone (pg/mL) 2 4 . 9 ± 1 3 . 4 1 0 . 8 ± 2 . 1 2 7 . 6 ± 1 2 . 9 <0.001

SBP: systolic blood pressure; DBP: diastolic blood pressure.