Clinical Study

BNP and Admission Glucose as In-Hospital Mortality Predictors in Non-ST Elevation Myocardial Infarction

Table 2

Clinical and demographic patient characteristics, grouped by BNP ≥ or < 300 pg/mL.

AllBNP < 300 pg/mLBNP ≥ 300 pg/mL 𝑃

Patients, 𝑛 (%)9663 (65.6)33 (34.4)
Age (years)*65.1 (11.7)62.9 (11.1)69.2 (12.0)0.012
Male, 𝑛 (%)64 (66.7)46 (73.0)18 (54.5)0.068
Prior coronary artery disease, 𝑛 (%)57 (59.4)34 (54.0)23 (69.7)0.136
Hypertension, 𝑛 (%)86 (89.6)54 (85.7)32 (97.0)0.086
Current smoker, 𝑛 (%)16 (16.7)12 (19.0)4 (12.1)0.387
Dyslipidemia, 𝑛 (%)65 (67.7)43 (68.3)22 (66.7)0.874
Diabetes mellitus, 𝑛 (%)48 (50)25 (39.7)23 (69.7)0.005
Family history of coronary artery disease, 𝑛 (%)35 (36.5)25 (39.7)10 (30.3)0.365
Heart rate (beats/minute)82.6 (27.6)75.6 (21.8)94.9 (32.4)0.001
Systolic blood pressure (mmHg)137.5 (30.8)144.5 (29.7)125.6 (29.3)0.005
Diastolic blood pressure (mmHg)83.1 (17.1)87.7 (16.7)75.2 (14.9)<0.001
Killip > I, 𝑛 (%)19 (19.8)4 (6.3)15 (45.5)<0.001
Admission glucose (mg/dL)152.4 (100.0)120.2 (46.9)213.9 (139.6)<0.001
Admission glucose ≥ 200 mg/dL, 𝑛 (%)19 (19.8)4 (6.3)15 (45.5)<0.001
BNP (pg/mL)358.3 (381.0)142.9 (87.6)769.6 (387.5)<0.001
Hemoglobin (g/dL)13.5 (2.1)14.1 (1.8)12.4 (2.2)<0.001
White blood cell count (/mm3)9879.6 (3418.4)9459.0 (3166.8)10681.3 (3775.9)0.102
Platelet count (/mm3)235244.7 (82837.8)232967.0 (71510.4)239455.0 (101620.0)0.719
Serum urea (mg/dL)52.7 (29.4)44.8 (19.0)67.5 (38.7)<0.001
Serum creatinine (mg/dL)1.33 (1.00)1.11 (0.39)1.76 (1.55)0.002
Creatinine kinase-MB (CKMB) peak (ng/mL)65.1 (111.1)60.1 (99.9)74.7 (131.0)0.542
Troponin I (ng/mL)25.8 (40.6)20.0 (32.7)36.9 (51.2)0.056
Cholesterol (mg/dL)175.0 (39.4)180.0 (37.9)165.5 (41.1)0.122
HDL-C (mg/dL)41.0 (10.9)40.9 (10.3)41.3 (12.1)0.886
LDL-C (mg/dL)110.6 (32.5)114.0 (31.3)103.7 (34.2)0.190
Triglycerides (mg/dL)130.4 (76.2)129.9 (65.3)131.1 (94.5)0.947
Ejection fraction (%)44.7 (15.3)49.3 (14.6)37.9 (13.9)0.001
Angiography, 𝑛 (%)86 (89.6)61 (96.8)25 (75.8)0.001
Medical therapy, 𝑛 (%)35 (36.5)18 (28.6)17 (51.5)0.027
Percutaneous coronary intervention, 𝑛 (%)49 (57.0)38 (62.3)11 (44.0)0.119
Surgery, 𝑛 (%)12 (12.5)7 (11.1)5 (15.2)0.570
Length of stay (days)10.5 (18.6)7.4 (14.7)16.4 (23.5)0.022
Followup (months)21.7 (9.7)22.7 (8.3)19.7 (11.9)0.143
Mortality, 𝑛 (%)17 (17.7)8 (12.7)9 (27.3)0.076
 In-hospital, 𝑛 (%)7 (7.3)2 (3.2)5 (15.2)0.032
 Followup, 𝑛 (%)10 (11.2)6 (9.8)4 (14.3)0.537
In-hospital mortality + prolonged length of stay, 𝑛 (%)25 (26.0)9 (14.3)16 (48.5)<0.001
Follow-up mortality + readmission, 𝑛 (%)51 (57.3)36 (59.0)15 (53.4)0.630