The Scientific World Journal

Research Article

Effect of Potent Ethyl Acetate Fraction of Stereospermum suaveolens Extract in Streptozotocin-Induced Diabetic Rats

Table 2

Effect of ethyl acetate fraction of stereospermum suaveolens on glucose level in STZ-induced diabetic rats.
GroupsSerum glucose levels (mg/dL)
1 day5th day7th day10th day15th day
Normal
(5% DMSO in 0.9% NaCl, 5 mL/kg )		85.64 ± 1.9985.84 ± 2.1887.84 ± 2.1891.64 ± 1.3686.60 ± 1.91
STZ-induced diabetic control (40 mg/kg) 2 9 0 . 6 5 ± 1 . 8 6 a,# 2 9 4 . 8 0 ± 2 . 3 5 a,# 2 9 4 . 8 4 ± 2 . 1 8 a,# 2 9 9 . 2 ± 1 . 4 6 a,# 2 9 3 . 4 0 ± 2 . 4 2 a,#
STZ + Ethyl acetate fraction (200 mg/kg) 2 6 4 . 8 1 ± 1 . 9 6 b,* 2 4 7 . 8 6 ± 1 . 8 6 b,** 2 1 1 . 8 4 ± 2 . 1 8 b,** 1 8 7 . 6 ± 2 . 1 8 b,** 1 2 9 . 4 2 ± 1 . 9 b,**
STZ+ Glibenclamide
(0.5 mg/kg)		 2 8 6 . 5 0 ± 6 . 3 5 1 7 3 . 5 0 ± 6 . 3 5 b,* 1 4 1 . 7 2 ± 6 . 2 6 b,* 1 2 6 . 2 1 ± 6 . 6 1 b,* 1 1 5 ± 6 . 1 1 b,*
Values are given as mean ± SEM, 6 rats in each group,
a , # 𝑃 < 0 . 0 0 1 as compared to normal control group,
b , ∗ 𝑃 < 0 . 0 5 , ∗ ∗ 𝑃 < 0 . 0 0 1 , when compared with STZ-treated control group.