The Scientific World Journal

Research Article

Effect of Potent Ethyl Acetate Fraction of Stereospermum suaveolens Extract in Streptozotocin-Induced Diabetic Rats

Table 3

Effect of ethyl acetate fraction of Stereospermum suaveolens on body weight in STZ-induced diabetic rats.
GroupsBody weight (g)
1st day4th day7th day10th day15th day
Normal (5% DMSO in 0.9% NaCl, 5 mL/kg) 1 8 5 . 7 3 ± 1 . 9 6 1 8 5 . 8 6 ± 1 . 3 2 1 9 6 . 0 0 ± 3 . 3 7 1 9 3 . 7 2 ± 3 . 2 4 1 9 7 . 2 6 ± 2 . 0 6
STZ-induced diabetic control (40 mg/kg) 1 8 1 . 2 5 ± 2 . 6 1 1 7 1 . 6 3 ± 2 . 7 0 a, # 1 6 4 . 8 1 ± 3 . 7 3 a, # 1 5 4 . 5 3 ± 2 . 7 4 a, # 1 5 4 . 1 3 ± 1 . 8 6 a,#
STZ + Ethyl acetate fraction (200 mg/kg) 1 8 2 . 6 0 ± 3 . 2 4 1 8 4 . 5 7 ± 0 . 6 4 b,** 1 8 9 . 1 2 ± 2 . 3 8 b,** 1 9 1 . 6 2 ± 2 . 2 9 b,** 1 9 4 . 5 7 ± 1 . 2 5 b,**
STZ + Glibenclamide (0.5 mg/kg) 1 8 4 . 0 6 ± 3 . 2 2 1 7 2 . 5 0 ± 0 . 8 4 1 6 9 . 1 3 ± 2 . 4 0 1 6 4 . 2 6 ± 2 . 2 1 1 5 9 . 5 6 ± 1 . 4 5
Values are mean ± SEM, 6 rats in each group,
a , # 𝑃 < 0 . 0 0 1 as compared to normal control group,
b , ∗ ∗ 𝑃 < 0 . 0 0 1 , when compared with STZ-treated control group.