Clinical Study

The rs2071559 AA VEGFR-2 Genotype Frequency Is Significantly Lower in Neovascular Age-Related Macular Degeneration Patients

Table 3

Differences of VEGFR-2 alleles and genotypes between controls and patients.

VEGFR-2 SNPsControlsAMDTotal

rs2071559*
 A89 (57.05%)107 (44.58%)196
 G67 (42.95%)133 (55.42%)200

Total156 (100%)240 (100%)396

rs1870377
 A31 (19.87%)63 (26.25%)94
 T125 (80.13%)177 (73.75%)302

Total156 (100%)240 (100%)396

rs2071559°
 AA27 (34.62%)22 (18.33%)49
 AG/GG51 (65.38%)98 (81.67%)149

Total78 (100%)120 (100%)198

rs2071559
 GG16 (20.51%)35 (29.17%)51
 AG/AA62 (79.49%)85 (70.83%)147

Total78 (100%)120 (100%)198

rs1870377
 AA3 (3.85%)10 (8.33%)13
 AT/TT75 (96.15%)110 (91.67%)185

Total78 (100%)120 (100%)198

rs1870377
 TT50 (64.10%)67 (55.84%)117
 AT/AA28 (35.90%)53 (44.16%)81

Total78 (100%)120 (100%)198

*P = 0.0153, 𝜒 2 , 𝑃 c o r r = 0 . 0 6 1 2 .
°P = 0.0095, 𝜒 2 , 𝑃 c o r r = 0 . 0 3 8 .