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The Scientific World Journal
Volume 2012 (2012), Article ID 451081, 7 pages
http://dx.doi.org/10.1100/2012/451081
Clinical Study

A Comparison of Third-Generation Semi-Invasive Arterial Waveform Analysis with Thermodilution in Patients Undergoing Coronary Surgery

1Department of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig-Holstein, 24105 Kiel, Germany
2Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany
3Department of Cardiothoracic and Vascular Surgery, University Hospital Schleswig-Holstein, 24105 Kiel, Germany
4ICU and High Care Burn Unit, ZNA, Campus Stuivenberg, 2060 Antwerpen, Belgium

Received 25 February 2012; Accepted 12 April 2012

Academic Editors: J. Alvarez, I. Misumi, E. Skalidis, and M. C. Vallejo

Copyright © 2012 Ole Broch et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Uncalibrated semi-invasive continous monitoring of cardiac index (CI) has recently gained increasing interest. The aim of the present study was to compare the accuracy of CI determination based on arterial waveform analysis with transpulmonary thermodilution. Fifty patients scheduled for elective coronary surgery were studied after induction of anaesthesia and before and after cardiopulmonary bypass (CPB), respectively. Each patient was monitored with a central venous line, the PiCCO system, and the FloTrac/Vigileo-system. Measurements included CI derived by transpulmonary thermodilution and uncalibrated semi-invasive pulse contour analysis. Percentage changes of CI were calculated. There was a moderate, but significant correlation between pulse contour CI and thermodilution CI both before ( π‘Ÿ 2 = 0 . 7 2 , 𝑃 < 0 . 0 0 0 1 ) and after ( π‘Ÿ 2 = 0 . 6 2 , 𝑃 < 0 . 0 0 0 1 ) CPB, with a percentage error of 31% and 25%, respectively. Changes in pulse contour CI showed a significant correlation with changes in thermodilution CI both before ( π‘Ÿ 2 = 0 . 5 2 , 𝑃 < 0 . 0 0 0 1 ) and after ( π‘Ÿ 2 = 0 . 6 7 , 𝑃 < 0 . 0 0 0 1 ) CPB. Our findings demonstrated that uncalibrated semi-invasive monitoring system was able to reliably measure CI compared with transpulmonary thermodilution in patients undergoing elective coronary surgery. Furthermore, the semi-invasive monitoring device was able to track haemodynamic changes and trends.