Immunohistological Localization of BMP-2, BMP-7, and Their Receptors in Knee Joints with Focal Cartilage Lesions

Table 3

Comparison between patients with different durations of complains (≤48 months 𝑛=7, >48 months 𝑛=8).

Criterion	Duration of symptoms		Significance (𝑃)
	≤48 months	>48 months
Age	39.22 ± 12.39	27.78 ± 6.732	0.0638*
Gender (f/m)	3/8	3/1	0.7552^#
ICRS score	3.43 ± 0.53	3.62 ± 0.52	0.4623*
Defect size	3.68 ± 1.34	3.97 ± 1.67	0.4437*
KOSS (MRI)	5.86 ± 1.57	8.25 ± 1.98	𝟎.𝟎𝟐𝟎𝟐^∗
Henderson score	2.00 ± 0.82	2.87 ± 1.36	0.1697*
Kellgren-Lawrence score	1.00 ± 0.58	0.87 ± 0.83	0.7023*
Duration of symptoms (months)	23.43 ± 16.36	76.50 ± 23.95	𝟎.𝟎𝟎𝟏𝟎^∗
Krenn score	2.00 ± 1.41	2.25 ± 1.03	0.5048*
BMP-2-Syn	2.28 ± 1.89	2.37 ± 2.06	1.0000*
BMP-2-C	2.43 ± 1.90	2.25 ± 1.58	0.9500*
BMPR-1A-Syn	5.00 ± 1.00	4.75 ± 0.89	0.6171*
BMPR-1A-C	2.57 ± 1.62	2.62 ± 2.37	0.9000*
Mankin score	8.00 ± 2.00	7.375 ± 3.02	0.8590*
Pritzker score	3.43 ± 0.79	3.62 ± 1.51	0.9497*

^∗𝑈-Test (Mann-Whitney), ^#Fisher exact test, f: female, m: male, Syn: synovia, C: cartilage.