Metabolic Basis for Thyroid Hormone Liver Preconditioning: Upregulation of AMP-Activated Protein Kinase Signaling

<table>Calorigenic response of thyroid hormone (T<sub>3</sub>) and its relationship with O<sub>2</sub> consumption, reactive oxygen species (ROS) generation, and antioxidant depletion in the liver. Abbreviations: CYP2E1, cytochrome P450 isoform 2E1; GSH, reduced glutathione; QO<sub>2</sub>, rate of O<sub>2</sub> consumption; SOD, superoxide dismutase.</table>

The Scientific World Journal

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Figure 2

Figure 2: Metabolic Basis for Thyroid Hormone Liver Preconditioning: Upregulation of AMP-Activated Protein Kinase Signaling 