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The Scientific World Journal
Volume 2012 (2012), Article ID 489830, 12 pages
Genetics and Epigenetics of Parkinson's Disease
1Faculty of Medicine, University of Pisa, 56126 Pisa, Italy
2Genetics and Epigenetics of Complex Disease Program, Department of Neuroscience (DAI Neuroscience), Pisa University Hospital, Via S. Giuseppe 22, 56126 Pisa, Italy
Received 15 October 2011; Accepted 21 December 2011
Academic Editors: H. Cui and M. Hiltunen
Copyright © 2012 Fabio Coppedè. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citations to this Article [33 citations]
The following is the list of published articles that have cited the current article.
- K. Gapp, B.T. Woldemichael, J. Bohacek, and I.M. Mansuy, “Epigenetic regulation in neurodevelopment and neurodegenerative diseases,” Neuroscience, 2012.
- Marina Spanos, Julie Gras-Najjar, Jeremy M. Letchworth, Audrey L. Sanford, J. Vincent Toups, and Leslie A. Sombers, “Quantitation of Hydrogen Peroxide Fluctuations and Their Modulation of Dopamine Dynamics in the Rat Dorsal Striatum Using Fast-Scan Cyclic Voltammetry,” ACS Chemical Neuroscience, vol. 4, no. 5, pp. 782–789, 2013.
- Jane S. Paulsen, Martha Nance, Ji-In Kim, Noelle E. Carlozzi, Peter K. Panegyres, Cheryl Erwin, Anita Goh, Elizabeth McCusker, and Janet K. Williams, “A review of quality of life after predictive testing for and earlier identification of neurodegenerative diseases,” Progress in Neurobiology, vol. 110, pp. 2–28, 2013.
- Jj Chen Jia-Jun, Mx Tian Ming-Xiu, Xa Li Xing-An, and Ls Hu Lin-Sen, “An Analysis of Protein Bioinformatics Datasets Related to Lewy Bodies of Parkinson's Disease,” Progress in Biochemistry and Biophysics, vol. 40, no. 11, pp. 1100–1106, 2013.
- Paul R. Heath, Oliver Bandmann, Janine Kirby, and Pamela J. Shaw, “Neuronal dark matter: the emerging role of microRNAs in neurodegeneration,” Frontiers in Cellular Neuroscience, vol. 7, 2013.
- Radu Constantinescu, and Stefania Mondello, “Cerebrospinal fluid biomarker candidates for Parkinsonian disorders,” Frontiers in Neurology, vol. 3, 2013.
- G. Natale, E. Pompili, F. Biagioni, S. Paparelli, P. Lenzi, and F. Fornai, “Histochemical approaches to assess cell-to-cell transmission of misfolded proteins in neurodegenerative diseases,” European Journal of Histochemistry, vol. 57, no. 1, pp. 31–35, 2013.
- Fabio CoppedÃ¨, “The potential of epigenetic therapies in neurodegenerative diseases,” Frontiers in Genetics, vol. 5, 2014.
- Kazunari Sekiyama, Yoshiki Takamatsu, Masaaki Waragai, and Makoto Hashimoto, “Role of genomics in tranaslational research for parkinson’s disease,” Biochemical and Biophysical Research Communications, 2014.
- Margherita Grasso, Paola Piscopo, Annamaria Confaloni, and Michela A. Denti, “Circulating miRNAs as Biomarkers for Neurodegenerative Disorders,” Molecules, vol. 19, no. 5, pp. 6891–6910, 2014.
- Nandhini Kanagaraj, He Beiping, S. Thameem Dheen, and Samuel Sam Wah Tay, “Downregulation of miR-124 in MPTP-treated mouse model of Parkinson’s disease and MPP iodide treated MN9D cells modulates the expression of the calpain/cdk5 pathway proteins,” Neuroscience, 2014.
- Ti-Fei Yuan, Jiang Li, and Chun-Lei Shan, “The Epigenetics Changes in Parkinson's Disease: a Novel Therapeutic Target,” CNS Neuroscience & Therapeutics, vol. 20, no. 4, pp. 299–300, 2014.
- Maria Teresa Baltazar, Ricardo Jorge Dinis-Oliveira, Maria de Lourdes Bastos, Aristidis M. Tsatsakis, José Alberto Duarte, and Félix Carvalho, “Pesticides exposure as etiological factors of Parkinson's disease and other neurodegenerative diseases—A mechanistic approach,” Toxicology Letters, 2014.
- Wei Xu, Lan Tan, and Jin-Tai Yu, “The link between the SNCA gene and parkinsonism,” Neurobiology of Aging, 2014.
- Ya Feng, Joseph Jankovic, and Yun-Cheng Wu, “Epigenetic mechanisms in Parkinson’s disease,” Journal of the Neurological Sciences, 2014.
- Fabio Coppedè, and Lucia Migliore, “DNA damage in neurodegenerative diseases,” Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2014.
- M Remely, L Lovrecic, A L de la Garza, L Migliore, B Peterlin, F I Milagro, A J Martinez, and A G Haslberger, “Therapeutic perspectives of epigenetically active nutrients,” British Journal of Pharmacology, 2014.
- Judith Eschbach, and Karin M. Danzer, “a-Synuclein in Parkinson's Disease: Pathogenic Function and Translation into Animal Models,” Neurodegenerative Diseases, vol. 14, no. 1, pp. 1–17, 2014.
- Xinling Yang, “Analysis of Thr12Met and Ala1144Thr Mutations of the ATP13A2 Gene in Parkinson’s Disease Patients in Xinjiang Uygur and Han Ethnic Groups,” Medical Science Monitor, vol. 20, pp. 2177–2182, 2014.
- Xinglong Yang, and Yanming Xu, “ Mutations in the ATP13A2 Gene and Parkinsonism: A Preliminary Review ,” BioMed Research International, vol. 2014, pp. 1–9, 2014.
- Smriti Gupta, Savita Verma, Shrikant Mantri, Nancy E. Berman, and Rajat Sandhir, “Targeting MicroRNAs in Prevention and Treatment of Neurodegenerative Disorders,” Drug Development Research, 2015.
- André V. Carreiro, Alexandre Mendonça, Mamede de Carvalho, and Sara C. Madeira, “Integrative biomarker discovery in neurodegenerative diseases,” Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2015.
- Chong-Dong Jian, Jian-Min Huang, Lan-Qing Meng, Xue-Bin Li, Rui-Ya Huang, Sheng-Liang Shi, Yuan Wu, Chao Qin, Jin Chen, Yan-Mei Zhang, Shuang Wang, Yin-Ling Feng, and Sheng-Nian Zhou, “ SNCA rs3822086 C>T Polymorphism Increases the Susceptibility to Parkinson's Disease in a Chinese Han Population ,” Genetic Testing and Molecular Biomarkers, pp. 150723112651005, 2015.
- Roy Lardenoije, Artemis Iatrou, Gunter Kenis, Konstantinos Kompotis, Harry W.M. Steinbusch, Diego Mastroeni, Paul Coleman, Cynthia A. Lemere, Patrick R. Hof, Daniel L.A. van den Hove, and Bart P.F. Rutten, “The Epigenetics of Aging and Neurodegeneration,” Progress in Neurobiology, 2015.
- Gabriela S. Longo, Marcela A. S. Pinhel, Michele L. Gregorio, Bruno A. P. Oliveira, Driele C. G. Quinhoneiro, Waldir A. Tognola, Fabio N. Oliveira, Sabrina M. Cezario, Caroline L. Sado, Marcelo A. Nakazone, Maria C. J. Calastri, and Doroteia R. S. Souza, “Alpha-synuclein A53T mutation is not frequent on a sample of Brazilian Parkinson's disease patients,” Arquivos De Neuro-Psiquiatria, vol. 73, no. 6, pp. 506–509, 2015.
- Lior Greenbaum, and Bernard Lerer, “Pharmacogenetics of Antipsychotic-Induced Movement Disorders as a Resource for Better Understanding Parkinsonâ€™s Disease Modifier Genes,” Frontiers in Neurology, vol. 6, 2015.
- Jorge Landgrave-GÃ³mez, Octavio Mercado-GÃ³mez, and Rosalinda Guevara-GuzmÃ¡n, “Epigenetic mechanisms in neurological and neurodegenerative diseases,” Frontiers in Cellular Neuroscience, vol. 9, 2015.
- Zhong-Kui Xiong, Juan Lang, Gang Xu, Hai-Yu Li, Yun Zhang, Lei Wang, Yao Su, and Ai-Jing Sun, “Excessive levels of nitric oxide in rat model of Parkinson's disease induced by rotenone,” Experimental And Therapeutic Medicine, vol. 9, no. 2, pp. 553–558, 2015.
- Rita Török, Dénes Zádori, Nóra Török, Éva Csility, László Vécsei, and Péter Klivényi, “An assessment of the frequency of mutations in the GBA and VPS35 genes in Hungarian patients with sporadic Parkinson's disease,” Neuroscience Letters, 2015.
- Afroza Khanam Irin, Alpha Tom Kodamullil, Michaela Gündel, and Martin Hofmann-Apitius, “Computational Modelling Approaches on Epigenetic Factors in Neurodegenerative and Autoimmune Diseases and Their Mechanistic Analysis,” Journal of Immunology Research, vol. 2015, pp. 1–10, 2015.
- Callie E. Todt, Denise C. Bailey, Aireal S. Pressley, Sarah E. Orfield, Rachel D. Denney, Isaac B. Snapp, Rekek Negga, Andrew C. Bailey, Kara M. Montgomery, Wendy L. Traynor, and Vanessa A. Fitsanakis, “Acute Exposure to a Mn/Zn Ethylene-bis-Dithiocarbamate Fungicide Leads to Mitochondrial Dysfunction and Increased Reactive Oxygen Species Production in Caenorhabditis elegans,” NeuroToxicology, 2016.
- Shashikanta Tarai, Arindam Bit, Helton José dos Reis, András Palotás, Albert Rizvanov, and Akalabya Bissoyi, “Stratifying Heterogeneous Dimension of Neurodegenerative Diseases: Intervention for Stipulating Epigenetic Factors to Combat Oxidative Stress in Human Brain,” BioNanoScience, 2016.
- Mako Ogino, Mayuko Ichimura, Noriko Nakano, Akari Minami, Yasuko Kitagishi, and Satoru Matsuda, “Roles of PTEN with DNA Repair in Parkinson’s Disease,” International Journal of Molecular Sciences, vol. 17, no. 6, pp. 954, 2016.