General and Electrophysiological Toxic Effects of Manganese in Rats following Subacute Administration in Dissolved and Nanoparticle Form

Table 1

Treatment scheme with group codes, doses and treatment times.

Group code	Treatment and dose
C3	3 weeks, untreated
VC3	3 weeks, distilled water, orally
MnL3	3 weeks 14.84 mg/kg b.w. MnCl2, orally
MnH3	3 weeks 59.36 mg/kg b.w. MnCl2, orally
C33	6 weeks, untreated*
VC33	3 weeks, distilled water, orally + 3 weeks HEC intratracheally
MnL33	3 weeks 14.48 mg/b.w. kg MnCL2, orally + 3 weeks MnO2 NPs 2.63 mg/kg b.w. intratracheally
MnH33	3 weeks 59.36 mg/b.w. kg MnCL2, orally + 3 weeks MnO2 NPs 2.63 mg/kg b.w. intratracheally
C6	6 weeks, untreated*
VC6	6 weeks, distilled water, orally
MnL6	6 weeks 14.84 mg/kg b.w. MnCl2, orally
MnH6	6 weeks 59.36 mg/kg b.w. MnCl2, orally

*C33 and C6 were two different groups of rats.