Table 2: Factors and their corresponding levels implemented for the construction of 𝐿 1 8 orthogonal array.

FactorLevels used, actual (coded)
Low (−1)Medium (0)High (+1)

Independent variables
A: addition of TEANoYes
B: concentration of Carbopol (% w/v)124
C: flux rate of polymeric solution (mL/min)123
D: stirring rate of stirrer (rpm)100300500
E: reaction time of beads into CaCl2 solution (min)53060
F: drying methodRoomRotary evaporatorOven
G: NaCl (% w/v)00.010.1
H: pH7.27.68.0