Review Article
A Comprehensive Review on Pharmacotherapeutics of Herbal Bioenhancers
Table 12
Effect of piperine on plasma concentration of ampicillin in rabbits [
95].
| Time (h) | Ampicillin (μg/mL) | Ampicillin + piperine (μg/mL) |
| 0.0 | 0 | 0 | 0.5 | 30.584 ± 0.38 | 35.481 ± 0.26 | 1.0 | 44.668 ± 0.32 | 251.188 ± 0.27 | 1.5 | 31.672 ± 0.49 | 188.364 ± 0.31 | 2.0 | 26.607 ± 0.37 | 84.139 ± 0.31 | 2.5 | 18.836 ± 0.38 | 66.834 ± 0.26 | 3.0 | 17.782 ± 0.32 | 35.481 ± 0.27 | 3.5 | 12.589 ± 0.31 | 33.496 ± 0.26 | 4.0 | 12.589 ± 0.32 | 26.607 ± 0.27 | 4.5 | 9.441 ± 0.26 | 26.607 ± 0.27 |
|
|
n = 6, mean ± SD, P < 0.05.
|