Review Article

A Comprehensive Review on Pharmacotherapeutics of Herbal Bioenhancers

Table 12

Effect of piperine on plasma concentration of ampicillin in rabbits [95].

Time (h)Ampicillin (μg/mL)Ampicillin + piperine (μg/mL)

0.000
0.530.584 ± 0.3835.481 ± 0.26
1.044.668 ± 0.32251.188 ± 0.27
1.531.672 ± 0.49188.364 ± 0.31
2.026.607 ± 0.3784.139 ± 0.31
2.518.836 ± 0.3866.834 ± 0.26
3.017.782 ± 0.3235.481 ± 0.27
3.512.589 ± 0.3133.496 ± 0.26
4.012.589 ± 0.3226.607 ± 0.27
4.59.441 ± 0.2626.607 ± 0.27

n = 6, mean ± SD, P < 0.05.