The Scientific World Journal

Research Article

Low-Dose Fluvastatin Prevents the Functional Alterations of Endothelium Induced by Short-Term Cholesterol Feeding in Rabbit Carotid Artery

Table 2

Antioxidant enzyme activities and total nitrite/nitrate levels in carotid artery tissues from all groups.
Control groupCholesterol groupCholesterol + fluvastatin group
SOD (U/g protein)1.56 ± 0.254.60 ± 0.41 +3.36 ± 0.12 *
Catalase (U/g protein)2.13 ± 0.340.74 ± 0.08 +1.24 ± 0.23
Total nitrite/nitrate (nmol/mg protein)723.90 ± 18.98308.80 ± 1.80 +705.20 ± 7.19 *
+ 𝑃 < 0 . 0 0 1 , control versus cholesterol and * 𝑃 < 0 . 0 5 , cholesterol versus cholesterol + fluvastatin in SOD, and + 𝑃 < 0 . 0 1 , control versus cholesterol in catalase antioxidant enzyme activities. + 𝑃 < 0 . 0 0 1 , control versus cholesterol and * 𝑃 < 0 . 0 0 1 cholesterol versus cholesterol + fluvastatin in total nitrite/nitrate ( N O 2 − / N O 3 − ) levels of carotid artery tissues. Data are given ± S.E.M. ANOVA followed by Bonferroni post hoc test. Data are expressed as means of five independent measurements using five animals in each group.