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The Scientific World Journal
Volume 2012, Article ID 712048, 6 pages
http://dx.doi.org/10.1100/2012/712048
Clinical Study

Cerebrospinal Fluid BACE1 Activity and Brain Amyloid Load in Alzheimer's Disease

1Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technische Universität München, Ismaninger Street 22, 81675 München, Germany
2Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Ismaninger Street 22, 81675 München, Germany

Received 17 October 2011; Accepted 2 November 2011

Academic Editors: E. Ghebremedhin and D. R. Thal

Copyright © 2012 Timo Grimmer et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [7 citations]

The following is the list of published articles that have cited the current article.

  • Liang-Hao Guo, Christine Westerteicher, Xin-Hui Wang, Martina Kratzer, Amalia Tsolakidou, Meizi Jiang, Timo Grimmer, Simon M. Laws, Panagiotis Alexopoulos, Hideaki Bujo, Alexander Kurz, and Robert Perneczky, “SORL1 genetic variants and cerebrospinal fluid biomarkers of Alzheimer’s disease,” European Archives of Psychiatry and Clinical Neuroscience, vol. 262, no. 6, pp. 529–534, 2012. View at Publisher · View at Google Scholar
  • Ann D. Cohen, Gil D. Rabinovici, Chester A. Mathis, William J. Jagust, William E. Klunk, and Milos D. Ikonomovic, “Using Pittsburgh Compound B for In Vivo PET Imaging of Fibrillar Amyloid-Beta,” Current State of Alzheimer's Disease Research and Therapeutics, vol. 64, pp. 27–81, 2012. View at Publisher · View at Google Scholar
  • Ross W. Paterson, Jamie Toombs, Catherine F. Slattery, Jonathan M. Schott, and Henrik Zetterberg, “Biomarker Modelling of Early Molecular Changes in Alzheimer’s Disease,” Molecular Diagnosis & Therapy, 2013. View at Publisher · View at Google Scholar
  • Daniel Alcolea, Maria Carmona-Iragui, Marc Suarez-Calvet, M. Belen Sanchez-Saudinos, Isabel Sala, Sofia Anton-Aguirre, Rafael Blesa, Jordi Clarimon, Juan Fortea, and Alberto Lleo, “Relationship Between beta-Secretase, Inflammation and Core Cerebrospinal Fluid Biomarkers for Alzheimer's Disease,” Journal of Alzheimers Disease, vol. 42, no. 1, pp. 157–167, 2014. View at Publisher · View at Google Scholar
  • Mary J. Savage, Daniel J. Holder, Guoxin Wu, June Kaplow, Judith A. Siuciak, and William Z. Potter, “Soluble BACE-1 Activity and sAβPPβ Concentrations in Alzheimer’s Disease and Age-Matched Healthy Control Cerebrospinal Fluid from the Alzheimer’s Disease Neuroimaging Initiative-1 Baseline Cohort,” Journal of Alzheimer's Disease, vol. 46, no. 2, pp. 431–440, 2015. View at Publisher · View at Google Scholar
  • Patricia Regina Manzine, Matheus da Silva Souza, and Márcia Regina Cominetti, “BACE1 levels are increased in plasma of Alzheimer's disease patients compared with matched cognitively healthy controls,” Personalized Medicine, 2016. View at Publisher · View at Google Scholar
  • Stavropoulou, Mavrofrydi, Saftig, and Efthimiopoulos, “Serum starvation induces BACE1 processing and secretion,” Current Alzheimer Research, vol. 14, no. 4, pp. 453–459, 2017. View at Publisher · View at Google Scholar