Research Article

Synthesis and Neuropharmacological Evaluation of Some Novel Quinoxaline 2, 3-Dione Derivatives

Table 3

Rota rod test.

GroupsFalling timeFecal pellets

Control 3 1 1 . 7 ± 0 . 6 6 6 7 4 ± 0 . 5 7 7 4
Ethidium
Bromide 1 1 3 . 7 ± 0 . 8 8 1 9 *** 1 . 6 ± 0 . 3 3 3 ***
Antioxidant 1 8 8 ± 1 . 0 9 5 *** 2 . 2 ± 0 . 2 ***
Comp2a 2 0 3 . 2 ± 0 . 9 6 9 5 *** 1 . 8 ± 0 . 2 ***
Comp2b 1 7 7 . 2 ± 1 . 5 6 2 *** 2 . 8 ± 0 . 3 7 4 2 *
Comp2c 2 1 2 . 2 ± 0 . 9 6 9 5 *** 1 . 8 ± 0 . 2 ***

𝑃 < 0 . 0 5 ; ***extremely significant; **moderately significant; *significant.