Acute Effects of Vardenafil on Pulmonary Artery Responsiveness in Pulmonary Hypertension

Table 1

Effects of monocrotaline treatment on rat body weight and cardiac weight. Results are expressed as mean ± s.e.mean. *Significantly different from control rat at 𝑃<0.05. Number of animals is indicated in parentheses. BW (0 days): body weight before injection; BW (21. day): body weight at 21 days after injection; LV + S: wet weight of left ventricle plus septum; RV, wet weight of right ventricle; RV/ LV + S: ratio of RV to LV + S.

	Control (𝑛=20)	MCT (𝑛=20)
BW (0 day, gr)	195 ± 18	170 ± 3
BW (21.day, gr)	317± 15	225 ± 3*
RV/BW (gr/kg)	0.57 ± 0.02	1.15 ± 0.03*
RV/LV + S	0.23 ± 0.01	0.59 ± 0.01*