Kinetic Analysis for Macrocyclizations Involving Anionic Template at the Transition State

Figure 11

Concentration of the reactants, products, and reaction intermediates versus time for kinetic model 6. [A]₀ = [B]₀ = 0.005 M, [Br⁻]₀ = 0.0025 M, 𝑘₁ = 10 M⁻¹ min⁻¹, 𝑘_1𝑐 = 4000 M⁻² min⁻¹, 𝑘₂ = 0.5 min⁻¹, and 𝑘_2𝑐 = 200 M⁻¹ min⁻¹.