Clinical Study
Elevation of Matrix Metalloproteinases in Different Areas of Ascending Aortic Aneurysms in Patients with Bicuspid and Tricuspid Aortic Valves
Table 4
Age differences and detection of MMPs and TIMPs in BAV and TAV patients aged ≥52 years.
| | Average (pg/mL) | BAV () | TAV () | | Concave | Convex | | Concave | Convex | |
| | MMP-1 | 0.001 ± 0.005 | 0.000 | n.s. | 0.005 ± 0.01 | 0.003 ± 0.006 | n.s. | | MMP-2 | 136.2 ± 61.1 | 104.7 ± 43.8 | n.s. | 105.7 ± 64.0 | 76.1 ± 33.1 | n.s. | | MMP-8 | 1.7 ± 1.9 | 10.8 ± 13.9 | 0.002 | 4.8 ± 8.2 | 8.9 ± 11.2 | n.s. | | MMP-9 | 6.7 ± 8.1 | 25.4 ± 37.8 | 0.01 | 14.6 ± 20.8 | 22.7 ± 31.3 | n.s. | | TIMP-1 | 201.8 ± 428.7 | 61.4 ± 30.1 | n.s. | 54.8 ± 30.7 | 114.2 ± 213.7 | n.s. | | TIMP-2 | 132.3 ± 50.8 | 141.9 ± 34.2 | n.s. | 111.1 ± 50.5 | 133.5 ± 55.6 | n.s. | | TIMP-3 | 11.2 ± 3.4 | 11.0 ± 7.1 | n.s. | 9.2 ± 3.3 | 6.4 ± 1.0 | 0.02 | | TIMP-4 | 0.24 ± 0.07 | 0.24 ± 0.11 | n.s. | 0.18 ± 0.10 | 0.16 ± 0.05 | n.s. |
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n.s.: not significant.
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