Large Scale Association Analysis for Drug Addiction: Results from SNP to Gene

Table 3

Summary of genome-wide significant genes at the gene level (𝑃value<1.0𝐸−5) and their top SNPs with 𝑃value<1.0𝐸−3.

Population	Substance dependence	Gene	Gene's P value	Top SNPs	SNP's P value
Black men	Opiates	NCK2	2.70𝐸−06	rs2377339	1.10𝐸−07
				rs7589342	1.45𝐸−04
				rs12995333	1.89𝐸−04
				rs12053259	2.31𝐸−04
				rs6747023	3.90𝐸−04
				rs879900	7.72𝐸−04
White men	Nicotine	DSG3	1.99𝐸−06	rs6701037	1.20𝐸−07
				rs1057302	3.93𝐸−07
				rs6425323	2.94𝐸−04
				rs1057239	3.35𝐸−04