Evaluation of Antioxidant, Immunomodulatory, and Cytotoxic Action of Fractions from Eugenia uniflora L. and Eugenia malaccensis L.: Correlation with Polyphenol and Flavanoid Content

Table 1

Flavonoid and total phenolic content and hemolytic activity of extracts from E. uniflora and E. malaccensis.

Extract	Total phenolic content (mgGAE/g)	Flavonoid content (mgQE/g)	Hemolysis (%)
E. uniflora
LEtOAc Fr.	2756 ± 15.5	84.3 ± 3.4	72.73 ± 0.96
Ln-BuOH Fr.	2492 ± 58.1	8.6 ± 0.9	1.9 ± 0.72
LH2O Fr.	2445 ± 15.5	2.1 ± 0.07	0
SEtOAc Fr.	2831 ± 23.0	31.2 ± 1.1	72.23 ± 0.68
Sn-BuOH Fr.	2365 ± 38.3	5.6 ± 0.4	2.1 ± 0.74
SH2O Fr.	2351 ± 12.3	2.9 ± 0.4	0
E. malaccensis
LEtOAc Fr.	1641 ± 31.9	40.7 ± 1.5	100
Ln-BuOH Fr.	565 ± 32.7	20.7 ± 6.6	100
LH2O Fr.	264 ± 9.5	2.0 ± 0.4	0
SEtOAc Fr.	2920 ± 24.4	5.8 ± 0.3	100
Sn-BuOH Fr.	2341 ± 36.5	2.9 ± 0.9	100
SH2O Fr.	2256 ± 37.3	0	3.39 ± 0.82

Legend: (LEtOAc Fr.): ethyl acetate fraction of leaves, (Ln-BuOH Fr.): butanol fraction of leaves, (LH₂O Fr.): aqueous fraction of leaves, (SEtOAc Fr.): ethyl acetate fraction of seeds, (Sn-BuOH Fr.): butanol fraction of seeds, and (SH₂O Fr.): aqueous fraction of seeds. Values are means ± SD (𝑛=3).