Roquefort Cheese Proteins Inhibit Chlamydia pneumoniae Propagation and LPS-Induced Leukocyte Migration

Table 1

HL cells were plated, grown, and infected with C. pneumoniae at MOI 1. Additions of the Roquefort cheese extract fraction with final concentrations of 0.12, 0.25, and 0.55 mg/mL were performed simultaneously with the bacterial pathogen inoculation. The cell monolayers were harvested after 72 hours incubation at 35°C in 5% CO₂ and infective progeny number was determined as described in Section 2. Infective progeny formation in U-937 cells infected with C. pneumoniae in the presence of cheese protein extract.

Cheese extract (mg/mL)	Infective progeny IFU/mL
0	2.4 × 10^5 ± 1.3
0.12	2.8 × 10^4 ± 0.9*
0.25	7.2 × 10^2 ± 2.1*
0.50	5.8 × 10^1 ± 2.7*

∗Significant changes as compared with control, 𝑃 ≤ 0.05.