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The Scientific World Journal
Volume 2013, Article ID 162384, 6 pages
Research Article

The Influence of γ-Ray Irradiation on the Mechanical and Thermal Behaviors of nHA/PA66 Composite Scaffolds

Research Center for Nano-Biomaterials, Analytical & Testing Center, Sichuan University, Chengdu 610064, China

Received 29 August 2013; Accepted 8 October 2013

Academic Editors: R. Adhikari and K. Ishikawa

Copyright © 2013 Fu You et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The aim of this study is to investigate the influence of sterilization process using γ-ray radiation on the melting behavior, crystallization behavior, thermal stability, and mechanical properties of nanohydroxyapatite/polyamide66 (nHA/PA66) scaffolds for bone tissue engineering. The results show that the melting temperature, degree of crystallization, thermal stability, and mechanical properties of the composite scaffolds increased with the enhancement of radiation doses from 25 kGy to 50 kGy, especially the irradiation dose of 50 kGy which imposed a remarkable effect on these properties. However, a reverse trend was found when the 100 kGy irradiation dose was applied. In general, a conclusion can be drawn that sterilization using γ-ray radiation with proper dose has no adverse effect on the properties of nHA/PA66 composite scaffolds.