Review Article

Oral Anticoagulant Therapy in Patients Receiving Haemodialysis: Is It Time to Abandon It?

Table 2

Contraindications for the use of oral anticoagulants [32].

(i) Increased risk of bleeding events—platelet function disorders, thrombocytopenia, von Willebrand disease, and haemophilia
(ii) Recent intracranial bleeding. Conditions predisposing to intracranial bleeding—cerebral artery aneurysms
(iii) Conditions predisposing to gastrointestinal, urinary, and respiratory tract bleeding
(iv) Surgical procedures within the central nervous system or the eye
(v) Increased risk of frequent falls—caused by a neurological or another condition
(vi) Severe liver failure, cirrhosis
(vii) Untreated or poorly controlled arterial hypertension
(viii) Pregnancy
(ix) Infective endocarditis or pericardial effusion
(x) Hypersensitivity to the active substance or any of the excipients
(xi) Dementia, psychoses, alcoholism, and other conditions in which compliance may not be satisfactory and when  anticoagulant treatment cannot be safely administered

End-stage renal-disease-associated items are bold.