Dual Silencing of Hsp27 and c-FLIP Enhances Doxazosin-Induced Apoptosis in PC-3 Prostate Cancer Cells

Figure 3

In situ detection of apoptotic cells in siRNA (Hsp27, c-FLIP, dual) transfected PC-3 cells after 48 hours at each dosage of doxazosin treatment (1, 10, and 25 μM). In situ detection of apoptotic cells in prostate cancer cells was performed by 3′-end labeling with digoxigenin-dUTP using terminal transferase.