Research Article
Association of FAS and FAS Ligand Genes Polymorphism and Risk of Systemic Lupus Erythematosus
Table 3
Genotype and allele frequencies of FAS A-670G and FASL C-844T polymorphisms in SLE patients and controls.
| | | SLE
| Control
| P value | Odds ratio
(95% CI) |
| | FAS A-670G | | | | | | AA, n (%) | 34 (32) | 37 (25) | 0.03 | 2.1 (1–4.1) | | AG, n (%) | 55 (52) | 73 (49) | 0.3 | 1.2 (0.7–2.2) | | GG, n (%) | 17 (16) | 39 (26) | | Ref = 1 | | A n (%) | 123 (58) | 147 (49) | 0.03 | 1.4 (1-2) | | G n (%) | 89 (42) | 151 (51) | | Ref = 1 | | FAS ligand C-844T | | | | | | CC, n (%) | 50 (47.2) | 51 (34.2) | 0.01 | 2.8 (1.2–6.2) | | CT, n (%) | 46 (43.4) | 80 (47) | 0.1 | 1.8 (0.8–4.2) | | TT, n (%) | 10 (9.4) | 28 (18.8) | | Ref = 1 | | C n (%) | 146 (69) | 162 (54) | 0.001 | 1.9 (1.3–2.7) | | T n (%) | 66 (31) | 136 (46) | | Ref = 1 |
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