The Role of Thiamine Pyrophosphate in Prevention of Cisplatin Ototoxicity in an Animal Model

Figure 2

Showing extensive loss of the normal microarchitecture of the organ of Corti, severe destruction of the outer hair cells (↑↑). (b) Showing decreased number of spiral ganglion neurons with cell changes (star), such as vacuolation of the cytoplasm (↑). (c) Showing shrinkage of the intermediate cells (↑), edema of stria, and swelling of the epithelial cells of Reissner’s membrane (↑↑).

(a)

(b)

(c)