Exercise-Induced Muscle Damage and Running Economy in Humans

Table 1

Comparison of the effects of the resistance exercise on running economy.

Study	Subjects	EIMD	Muscle damage	VO2max (%)	RE (%)
Paschalis et al. [10]	10 healthy males	120 eccentric actions	↑ CK,; ↑ DOMS, and; ↓ ROM, and; ↓ strength	55 and 75	√
Burt et al. [12]	9 healthy men	100 squats at 80% body mass	√ CK,; ↑ DOMS, and; ↓ strength	90	↓ 4-5
Vassilis et al. [87]	24 young healthy men	120 eccentric actions	↑ CK,; ↑ DOMS,; ↓ strength	70	√
Scott et al. [88]	8 active men and; 8 active women	3-4 × 10 repetitions of squat, lunges, step up and step down, and stiff-legged deadlift	↑ DOMS	70	√

EIMD: exercise-induced muscle damage; %VO₂max: exercise intensity at which running economy was measured; RE: running economy; CK: creatine kinase; DOMS: delayed onset muscle soreness; ROM: range of motion; ↓ indicates decrease; √ indicates no change; ↑ indicates increase.