Association, Haplotype, and Gene-Gene Interactions of the HPA Axis Genes with Suicidal Behaviour in Affective Disorders

Table 6

Comparison of haplotype frequencies for the analysed AVPR1b polymorphisms between patients with suicide attempts and the control group.

Haplotype	Haplotype frequency	Case : control ratio	𝜒^2	𝑃
Block 1
AGG	0.823	0.814 : 0.826	0.291	0.589
GGG	0.076	0.068 : 0.079	0.547	0.459
GCA	0.060	0.081 : 0.052	4.087	0.043 *
GGA	0.041	0.037 : 0.042	0.162	0.687

∗Not significant after correction for multiple test using 10.000 permutations (𝑃=0.130).