The Scientific World Journal / 2013 / Article / Sch 1

Research Article

Synthesis and Biological Evaluation of 2-Hydroxy-3-[(2-aryloxyethyl)amino]propyl 4-[(Alkoxycarbonyl)amino]benzoates

Scheme 1

Synthesis of evaluated compounds. Reagents and conditions: (a) acetone, pyridine; (b) SOCl2, toluene; (c) 2,3-epoxypropan-1-ol, THF, and TEA; (d) 1,2-dibromoethane, NaOH; (e) potassium phthalimide, KI, and DMF; (f) NH2NH2 H2O, ethanol; (g) propan-2-ol; (h) HCl, Et2O.

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