Effect of Creatine Monohydrate Supplementation on Various Hematological and Serum Biochemical Parameters of Male Albino Mice following Neonatal Hypoxia-Ischemia Encephalopathy

Table 3

Comparison of various hematological and serum biochemical parameters between 2% creatine monohydrate treated and untreated (control) male albino mice for 15 weeks following hypoxia and ischemia: data is expressed as mean ± standard deviation.

Parameters	Creatine monohydrate treated Group		Untreated control group		𝑃 value
	Mean ± SD	Range	Mean ± SD	Range
Hematological profile
WBC (×10^9/L)	9.94 ± 5.64	3.2–17.4	9.94 ± 1.66	7.4–11.8	0.806 ns
RBC (×10^12/L)	7.512 ± 0.963	6.25–9.03	7.55 ± 2.98	2.77–10.58	0.977 ns
PCV%	31.5 ± 13.1	13.5–52.3	29.11 ± 9.66	14.2–41.6	0.681 ns
Glucose (mg/dL)	177.8 ± 18.4	150–205	211 ± 21	176–245	0.006**
MCV (fp)	42.5 ± 17.2	15–71.6	53.9 ± 47.9	13.4–150	0.570 ns
Serum biochemical profile
Total protein (g/dL)	3.83 ± 0.93	2.5–5	2.80 ± 1.66	1.6–4.7	0.423 ns
Triglycerides (mg/dL)	210 ± 146	59–399	331 ± 79.2	240–399	0.188 ns
Cholesterol (mg/dL)	178 ± 131	75–399	315 ± 192	129–513	0.356 ns
HDL (mg/dL)	31.00 ± 3.00	28–34	28.00 ± 8.00	20–36	0.605 ns
LDL (mg/dL)	69.7 ± 46.0	25–117	221 ± 169	60–397	0.110 ns
ASAT (𝜇/L)	227.7 ± 60.1	162–280	608 ± 330	144–889	0.110 ns
ALAT (𝜇/L)	40.8 ± 30.6	20–86	100.5 ± 76.2	42–208	0.242 ns

𝑃<0.05 = non-significant (ns), ^∗∗𝑃>0.01 = significant.