Research Article

Effect of Creatine Monohydrate Supplementation on Various Hematological and Serum Biochemical Parameters of Male Albino Mice following Neonatal Hypoxia-Ischemia Encephalopathy

Table 4

Comparison of various hematological and serum biochemical parameters between 2% creatine monohydrate treated and untreated (control) male albino mice for 12 weeks: data is expressed as mean ± standard deviation.

ParametersCreatine monohydrate treated group
( )
Untreated control group
( )
value
Mean ± SDRangeMean ± SDRange

Hematological profile
 WBC ( /L)4.3 ± 1.52.5–8.58.3 ± 2.64.6–13.30.302 ns
 RBC ( /L)5.69 ± 3.142.9–13.85.85 ± 2.672.1–10.50.903 ns
 PCV%25.13 ± 5.5817.3–34.828.0 ± 10.111.4–45.50.467 ns
 Glucose (mg/dL)146.4 ± 23.2107–193156.1 ± 60.578–2890.659 ns
 MCV (fp)55.1 ± 27.312.3–97.261.0 ± 45.320.1–1500.740 ns
Serum biochemical profile
 Total protein (g/dL)5.27 ± 1.233.9–6.340.9 ± 27.912.5–78.80.084 ns
 Triglycerides (mg/dL)226.3 ± 16.2216–245395.0 ± 93.8334–5030.092 ns
 Cholesterol (mg/dL)376 ± 283176–791765 ± 118629–8390.068 ns
 HDL (mg/dL)35.75 ± 9.2223–4520.67 ± 2.0819–230.051 ns
 LDL (mg/dL)152.6 ± 64.7735–742666 ± 10794–2220.006**
 ALAT ( /L)55.33 ± 5.0350–6081.00 ± 3.6178–850.006**
 ASAT (u/L)215.7 ± 46.7165–257157.33 ± 6.35150–1610.165 ns

= non-significant (ns), = significant.