Metal Complexes of Macrocyclic Schiff-Base Ligand: Preparation, Characterisation, and Biological Activity

Table 4

Biological activity for Schiff-base macrocyclic ligand and its complexes.

Compounds	Staphylococcus aureus (+)		Escherichia coli (−)		Pseudomonas aeruginosa (−)
	5 mM	10 mM	5 mM	10 mM	5 mM	10 mM
Free ligand	−	+	−	+	−	−
[Mn^II4(L)]Cl4; [Co^II4(L)]Cl4	++	+++	+	++	−	−
[Ni^II4(L)]Cl4	++	+++	+	++	−	−
[Cu^II4(L)]Cl4	++	+++	+	++	−	−
[Zn^II4(L)]Cl4	−	+	++	+++	−	−

(−): No inhibition/inactive, (+): (3–5) mm/active, (++): (6–8) mm/more active, (+++): (9–14) mm/highly active.