Research Article

Von Willebrand Factor Antigen Predicts Response to Double Dose of Aspirin and Clopidogrel by PFA-100 in Patients Undergoing Primary Angioplasty for St Elevation Myocardial Infarction

Table 3

Multivariate logistic regression for association with HPR (CEPI-CT 190 sec) at T1.

Variable Univariate analysis: value/Chi square ( value) Multivariate analysis: Chi square ( value)

Gender 1.068 (0.30)
Age 0.804 (0.37)
BMI 0.175 (0.67)
LVEF 0.766 (0.46)
Current smoking 0.589 (0.44)
LDL-Cholesterol > 130 mg/dL 3.102 (0.08)
Diabetes mellitus 3.363 (0.05) 9.151 ( 0.001)
Hypertension 9.496 (0.001)
Number of diseased vessels > 1 1.403 (0.27)
Number of treated vessels > 1 1.117 (0.31)
PPI* use 3.602 (0.06)
Platelets 1.833 (0.18)
High sensitivity RCP 1.221 (0.34)
Fibrinogen 11.347 (0.001)
Creatininine 0.769 (0.47)
VWF 36.115 ( 0.001) 6.873 (0.001)
ADAMTS-13 9.078 (0.003)

BMI: body mass index; LVEF: left ventricular ejection fraction; *Proton Pump Inhibitors.