Clinical Study
Polymorphisms but Not Mutations of the KCNQ1 Gene Are Associated with Lone Atrial Fibrillation in the Chinese Han Population
Table 3
Twelve known polymorphisms found in LAF patients.
| SNPs | Regions | Minor allele | Amino acid change | Han Chinese MAF |
| rs1800170 | Exon2 | T | I145I | 0.091 | rs59233444 | Intron2 | GG | — | N.A | rs12786951 | Intron6 | G | — | 0.489 | rs12577654 | Intron12 | T | — | 0.057 | rs760419 | Intron12 | G | — | 0.318 | rs163160 | Intron12 | G | — | 0.244 | rs2075870 | Intron12 | A | — | 0.170 | rs1057128 | Exon13 | A | S546S | 0.289 | rs163150 | Intron14 | A | — | 0.289 | rs2519184 | 3′-UTR | A | — | 0.034 | rs45510192 | 3′-UTR | A | — | N.A | rs394656 | 3′-UTR | C | — | N.A |
|
|
MAF (minor allele frequency) of Han Chinese is based on HapMap Data; N.A: not available from HapMap Data for Han Chinese population.
|