Elevated Preoperative Serum CA19-9 Levels in Patients with Hepatocellular Carcinoma Is Associated with Poor Prognosis after Resection

Table 2

Univariate analysis of overall survival for clinicopathological parameters.

Clinicopathological features	Hazard ratio (HR)	95% CI for HR		𝑃 value
		Lower	Upper
Age (<55 versus ≥55)	0.84	0.54	1.27	0.3943
Gender (Male versus Female)	1.18	0.70	1.94	0.5317
HBV infection ((−) versus (+))	1.14	0.75	1.75	0.5403
HCV infection ((−) versus (+))	0.89	0.57	1.41	0.6468
AFP (<200 ng/mL versus >200 ng/mL)	1.93	1.16	3.20	0.0031
CA19-9 (≤27 U/mL versus >27 U/mL)	1.87	1.21	2.90	0.0020
Grade (1, 2 versus 3, 4)	2.16	1.39	3.34	0.0001
Size (<5 cm versus ≥5 cm)	2.04	1.33	3.13	0.0004
Vascular invasion ((−) versus (+))	1.70	1.09	2.66	0.0094
Multiple ((−) versus (+))	1.79	1.11	2.87	0.0060
Stage (I versus II, III)	1.76	1.17	2.65	0.0057