The Role of Clomipramine in Potentiating the Teratogenic Effects of Caffeine in Pregnant Rats: A Histopathological Study
Figure 1
Macroscopic view of 17-day-fetuses from control group (a) and the group that received a combination of clomipramine and caffeine in high doses (b). In the control group fetus, the muzzle is formed normally. The body is C-shaped and eyes, ears, and upper and lower extremities are in their normal locations. The skin is taut (a). In the fetus from the group treated with clomipramine and caffeine in high doses, the body is not fully C-shaped, the forelimbs are bent, and corrugated skin and areas of subcutaneous hemorrhage are obvious (b).
