The Scientific World Journal / 2013 / Article / Tab 3

Research Article

Emergent Biomarkers of Residual Cardiovascular Risk in Patients with Low HDL-c and/or High Triglycerides and Average LDL-c Concentrations: Focus on HDL Subpopulations, Oxidized LDL, Adiponectin, and Uric Acid

Table 3

Markers of inflammatory and angiogenic profile of the populations under study.

Parameters(1) Effects of TGs levels (normal versus high) on normal and low HDL-c conditions/populations  (2) Effects of HDL-c levels (normal versus high) on normal and high TGs conditions (3) Effects of variations of both HDL-c and TGs levels
Normal HDL-c ( )Low HDL-c ( )
Normal TGs ( ) Population AHigh TGs ( ) Population B
A versus B
Normal TGs ( ) Population CHigh TGs ( ) Population D
C versus D
(Normal TGs) (A versus C)(High TGs)   
(B versus D)

A versus D

B versus C

CRP (µg/mL) 0.798 0.9810.2060.2370.1310.327
TNF- (pg/mL) 0.727 0.7580.9140.5520.5730.858
iCAM-1 (ng/mL) 0.664 0.0640.5250.2150.0010.975
Adiponectin (µg/mL) 0.108 0.0100.6970.1100.0000.201
Uric acid (mmol/L) 0.005 0.0230.1040.6160.1440.005
VEGF (pg/mL) 0.161 0.7590.1130.3020.0170.564

Results are presented as media ± SEM. Independent samples -test and Mann-Whitney test for normalized and nonnormalized samples, respectively. CRP: C-reactive protein; iCAM-1: intercellular adhesion molecule 1; TNF- : tumour necrosis factor alpha; VEGF: vascular endothelial growth factor.

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