Sequential Oxygenation Index and Organ Dysfunction Assessment within the First 3 Days of Mechanical Ventilation Predict the Outcome of Adult Patients with Severe Acute Respiratory Failure
Table 1
Baseline characteristics of patients.
Characteristics
Age (years)
72.14 (15.77)
Gender ( (%))
Male
58 (58)
Female
42 (42)
Hospital duration (days)
38.1 (30.5)
Hospital mortality ( (%))
38 (38)
SOFA* score on admission
4.71 (2.71)
APACHE* II score
25.82 (6.74)
Source ( (%))
Emergency department
55 (55)
Hospital ward
38 (38)
Other ICU* or other hospitals
7 (7)
Previous MICU* admission ( (%))
30 (30)
Comorbidities ( (%))
Congestive heart failure
10 (10)
Hypertension
62 (62)
Chronic obstructive pulmonary disease
22 (22)
Pulmonary tuberculosis
9 (9)
CRF* with tracheostomy
11 (11)
Liver cirrhosis
10 (10)
Chronic kidney disease
19 (19)
Diabetes mellitus
35 (35)
Cerebrovascular accident
30 (30)
Hepatitis B
6 (6)
Hepatitis C
4 (4)
Cancer history
22 (22)
Respiratory and ventilator parameters
Fi day1
0.58 (0.21)
Pa day 1 (mmHg)
140.46 (88.21)
PEEP* day 1 (cmH2O)
5.55 (2.63)
mPaw* day 1 (cmH2O)
11.99 (3.23)
PaO2/FiO2 day 1 (mmHg)
267.95 (181.11)
OI* day 1 (cmH2O/mmHg)
7.06 (6.01)
FiO2 day 3
0.43 (0.16)
PaO2 day 3 (mmHg)
109.79 (32.84)
PEEP day 3 (cmH2O)
5.8 (2.65)
mPaw day 3 (cmH2O)
11.46 (3.02)
PaO2/FiO2 day 3 (mmHg)
287.92 (116.3)
OI day 3 (cmH2O/mmHg)
5.74 (5.82)
OI change from day 1 to day 3
−1.31 (6.34)
*APACHE: Acute Physiological Assessment and Chronic Health Evaluation, CRF: chronic respiratory failure, FiO2: fraction inspired oxygen, ICU: intensive care unit, MICU: medical intensive care unit, mPaw: mean airway pressure, OI: oxygenation index, PaO2: arterial oxygen tension, PEEP: positive end expiratory pressure, SOFA: Sequential Organ Failure Assessment. Variables are expressed as mean (standard deviation) and categorical data are expressed as number (percentage).
