Research Article

Low Density Solvent-Based Dispersive Liquid-Liquid Microextraction for the Determination of Synthetic Antioxidants in Beverages by High-Performance Liquid Chromatography

Table 2

Comparison of the proposed DLLME method with other methods used in determination of antioxidants.

MethodSampleVolumeAnalytesExtraction time (min)LR
(µg L−1)
LOD
(ng mL−1)
RSD
(%)
Ref.

SPME-GC-MSaDrinking water15 mLBHT30 min12.8–64.00.9984.27–14[30]

SPE-GC-MSbRiver water5 LBHT0.0016[15]

O-CLLE-GC-MScEffluent samples40 LBHA
BHT
<23 min0.025–1
0.0125–0.5
0.994
0.993
0.01
0.008
19.7
34.3
[14]

SPE-GC-MSAqueous samples200 mLTBHQ
BHA
BHT
2–2000
2–2000
2–2000
0.996
0.994
0.997
0.03
0.8
0.2
2
3
4
[1]

DLLME-HPLC-UVdFruit
juice
40 mLBHA
BHT
10 min10–2500
2–2500
0.9993
0.9989
2.5
0.9
2.7
4.2
[9]

DLLME-HPLC-UVBeverages5 mLTBHQ
BHA
BHT
<1 min5–1000
5–1000
50–1000
0.9980
0.9997
0.9975
0.85
1.67
2.73
1.0
2.2
5.2
This study

Solid-phase microextraction-gas chromatography-mass spectrometry.
Solid-phase extraction-gas chromatography-mass spectrometry.
Online continuous liquid-liquid extraction-gas chromatography-mass spectrometry.
Dispersive liquid-liquid microextraction high-performance liquid chromatography-ultraviolet detection.