Reactive Oxygen Species Production in Peripheral Blood Neutrophils of Obstructive Sleep Apnea Patients
Table 2
Characteristics of obese and nonobese men with mild-to-moderate and severe obstructive sleep apnea.
Variable
Nonobese mild-to-moderate OSA ()
Obese mild-to-moderate OSA ()
Nonobese severe OSA ()
Obese severe OSA ()
Age (yearns)
45.5 (41–48)
43.0 (39–46)
48.0 (32–54)
37.0 (34–48)
Epworth Sleepiness Scale
10.5 (4.0–12.0)
10.0 (5.5–12.5)
10.0 (4.0–15.0)
11.0 (10.0–17.0)
BMI (kg/m2)
28.2 (28.1–28.7)†#
34.1 (31.3–38.4)*¥
28.4 (27.5–29.8)†#
37.4 (33.8–38.7)*¥
Waist (cm)
100 (95–102)†#
115 (110–118)*¥
97 (96–101)†#
118 (112–126)*¥
Polysomnographic parameters:
AHI (events/h)
12.7 (8.5–19.9)¥#
16.2 (9.1–19.4)¥#
53.5 (35.5–59.4)*†#
65.3 (74.2–91.4)*†¥
Arousal index (events/h)
21.7 (18.9–27.5)¥#
19.9 (14.5–24.3)¥#
38.2 (33.4–59.4)*†#
59.1 (48.5–79.9)*†¥
Oxygen desaturation index (events/h)
11.5 (7.1–13.7)¥#
15.6 (9.9–18.9)¥#
48.8 (27.1–56.3)*†#
76.1 (72.2–78.9)*†¥
Average SpO2 (%)
96.0 (94.0–96.0)#
94.5 (94.0–95.5)#
95.0 (93.0–95.0)#
91.0 (87.5–92.0)*†¥
Total sleep time SpO2 < 90% (%)
0.1 (0–1.4)#
0.8 (0.3–2.0)#
5.3 (2.5–7.2)#
34.5 (23.2–53.2)*†¥
Lipid profile:
Total cholesterol (mmol/L)
5.90 (4.92–6.64)
5.64 (5.29–6.69)
5.46 (4.91–6.07)
5.15 (4.93–6.24)
High-density lipids (mmol/L)
1.01 (0.96–1.05)
0.76 (0.70–0.86)
0.95 (0.81–1.20)
0.91 (0.80–1.02)
Low-density lipids (mmol/L)
3.84 (3.37–4.86)
3.74 (3.61–4.51)
3.22 (3.05–3.71)
3.75 (3.32–3.94)
Triglycerides (mmol/L)
1.14 (0.86–2.41)
2.06 (1.84–2.67)
1.22 (0.85–2.56)
1.70 (1.19–2.92)
Data is presented as median (25th and 75th percentiles). Comparisons of variables among four groups were made with Kruskal-Wallis test, followed by Bonferroni test. OSA: obstructive sleep apnea. * versus nonobese mild-to-moderate OSA, † versus obese mild-to-moderate OSA, ¥ versus nonobese severe OSA, # versus obese severe OSA.
