Research Article

Association between TLR4 and TLR9 Gene Polymorphisms with Development of Pulmonary Tuberculosis in Zahedan, Southeastern Iran

Table 4

TLR9-1486T/C genotype and allele frequencies in patients and controls.

SNP
PTB patients ( = %)Controls ( = %) value*OR (95% CI)

TLR9 (T-1486C)
 TT63 (51)82 (55)
 TC51 (41)59 (39.6)0.20.41.1 (0.7–1.9)
 CC10 (8)8 (5.4)10.21.6 (0.6–4.4)

 Total124 149

 T177 (71.4)223 (74.8)
 C71 (28.6)
75 (25.2)0.8
0.21.2 (0.8–1.8)

*Compared with healthy controls. A corrected value < 0.05 was considered significant.